Paradigm Biopharma’s portfolio centers on pentosan polysulfate sodium (PPS)

Paradigm Biopharma’s portfolio centers on pentosan polysulfate sodium (PPS), a repurposed drug with proven efficacy in treating a range of diseases. PPS has long been used to treat bladder pain and inflammation, but Paradigm is working to expand its application into various other therapeutic areas, including osteoarthritis and other musculoskeletal conditions, as well as rare diseases. The company is exploring the potential of PPS to address both the underlying causes and symptoms of diseases, rather than just managing symptoms. Pentosan polysulfate sodium is the cornerstone of Paradigm’s therapeutic pipeline. The drug works by modulating the immune system and reducing inflammation. PPS’s unique mechanism of action makes it suitable for a range of chronic pain and inflammatory conditions, as it has been shown to:Reduce Inflammation: By targeting inflammatory pathways, PPS helps reduce pain and inflammation in conditions such as osteoarthritis and other musculoskeletal disorders.